BED方法监测吸毒人群HIV新发感染率

Surveillance of New HIV Infections in Drug Users by BED Method

目的监测估计四川省吸毒人群艾滋病(HIV)新发感染率。方法收集2007-2012年四川省13个吸毒人群监测哨点HIV筛查阳性样本,进行蛋白印迹法(Western Blot,简称WB)确证检测,对其中阳性样本排除既往感染后,进行BED方法检测,进而计算各地区和全省新发感染率。结果 2007-2012年四川省吸毒哨点HIV新发感染率分别为7.62%、3.45%、2.92%、1.57%、1.52%和1.17%,其中累计存活HIV/AIDS大于2万(人群感染率大于5‰)的高流行地区连续6年新发感染率为24%、7.81%、15.56%、8.05%、10.12%和6.21%。结论四川省吸毒人群HIV新发感染率逐年下降,但是高流行地区HIV流行形式依然严峻,可以认为全省综合防治工作已取得相当成效,但重点地区仍需持续加强工作力度。

Objective To survey and estimate the incidence of HIV in injection drug use （IDU） population in Sichuan province. Methods Preliminary screened HIV positive samples of 13 IDU sentinels during 2007 to 2012 were collected and tested by Western Blot （WB）. The positive samples were assayed using the BED method. The incidence of HIV in IDU sentinel populations were further estimated in each district and across the province. Results The HIV incidences during 2007 to 2012 in IDU sentinels in Sichuan were 7.62%, 3.45% , 2. 92% , 1.57% , 1.52% and 1.17% , respectively. The incidences of the severely endemic areas （with infection rate over 5%~） were correspondingly 24%, 7.81%, 15.56%, 8.05%, 10. 12% and 6. 21%. Conclusion The HIV incidences in IDU population of Sichuan have decreased year after year; nevertheless, the epidemic situation is still rigorous in high prevalence areas, which requires strengthened prevention and control efforts.