顺德区龙江地区2013年25例登革热患者临床分析

Clinical analysis of 25 patients with dengue fever in Shunde district of Foshan city in 2013

目的探讨2013年佛山市顺德龙江地区登革热病例的临床及实验室特征,为临床诊治提供依据。方法对龙江地区2013年新发25例登革热患者临床与实验室资料进行回顾性分析。结果登革热患者主要临床表现为发热(100%)、头痛(76%)、肌痛(76%)、皮疹或出血点(60%)。分别有48%和24%的患者出现白细胞计数减少与血小板计数下降。20%的患者丙氨酸转氨酶水平升高,64%的患者出现天冬氨酸转氨酶升高,男性高于女性。同时,有48%的患者乳酸脱氢酶升高和20%的患者出现肌酸磷酸肌酶升高。结论佛山龙江地区本次登革热为多点散发的本地疫情,患者临床症状较轻,部分患者出现肝脏损害及心肌损伤,经积极治疗临床恢复较好。

Objective To investigate the clinical and laboratory features of cases with dengue fever. Methods The data of 25 cases with dengue fever in Shunde Longjiang area of Foshan in 2013 were retrospectively analyzed. Results The major clinical manifestations of the cases were fever （100%）, headache（76% ）, myalgia （76%）, rash or hemorrhage（60% ）. Reduction of white blood cell count and platelet count were noticed in 48% and 24% of patients, the level of alanine aminotransferase rised in 20% of the patients and the level of aspartate aminotransferase was increased in 64% of patients being higher in the male than that of female. Meanwhile the levels of lactate dehydrogenase and creatine kinase were increased in 48% and 20% of the patients. Conclusion The dengue fever cases were sporadically distributed in Longjiang area of Foshan city, The clinical symptoms were lighter, liver damage and myocardial damage occurred to some patients, but recovered after active treatment.