老年2型糖尿病患者治疗过程中发生严重低血糖的危险因素

Analysis on the risk factors of serious hypoglycemia in elderly patients with type 2 diabetes

目的考察老年2型糖尿病患者治疗过程中发生严重低血糖的危险因素。方法选择2013年5月-2014年5月收治的发生严重低血糖的糖尿病患者100例并设为观察组,并选取同期收治的未发生严重低血糖的糖尿病患者100例作为对照组,比较两组患者的临床资料,并分析出现严重低血糖的影响因素。结果两组患者的年龄、病程、体重指数（BMI）、血清肌酐（Cr）、尿微量清蛋白（UMA）比较,差异有统计学意义（P〈0.05,P〈0.01）;经Logistic多元回归分析检测,年龄（OR=1.81,P〈0.01）、BMI（OR=0.65,P〈0.05）和UMA（OR=2.39,P〈0.05）是严重低血糖发生的危险因素,其中高BMI是2型糖尿病患者发生严重低血糖的保护性因素,而年龄和UMA则是危险因素。结论2型糖尿病治疗过程中的严重低血糖是多种因素共同作用的结果,减少危险因素并针对性地进行护理有助于降低严重低血糖的发生。

Objective To analyze the risk factors of serious hypoglycemia in elderly patients with type 2 diabetes.Methods 100 patients with type 2 diabetes occurred serious hypoglycemia from May 2013 to May 2014 were selected as observation group and 100 patients with type 2 diabetes without serious hypoglycemia from May 2013 to May 2014 were selected as control group.The clinical data was compared and analyzed to indicate the risk factors of serious hypoglycemia. Results There was significant difference of age,disease duration,body mass index（BMI）,serum creatinine（Cr）,urine micro albumin（UMA） between the two groups（P〈0.05,P〈0.01）.Logistic regression analysis indicated that,age（OR=1.81,P〈0.01）,BMI（OR=0.65,P〈0.05） and UMA（OR=2.39,P〈0.05） were the risk factors for serious hypoglycemia.The high BMI was a protective factor for serious hypoglycemia,the age and UMA were the risk factors for serious hypoglycemia. Conclusion Serious hypoglycemia during the treatment of elderly patients with type 2 diabetes is the result of many factors,reducing risk factors or adjusted treatment and nursing is the key to reducing the incidence of serious hypoglycemia.