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立普妥片联合普罗布考片治疗颈动脉粥样硬化斑块的疗效观察 被引量:5

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摘要 目的:观察口服立普妥片联合普罗布考片治疗对颈动脉内膜动脉粥样硬化斑块的作用。方法:随机抽取经颈部彩色多普勒超声检查确定为颈动脉粥样硬化患者68例,随机分为治疗组和对照组:治疗组选取32例患者给予口服立普妥片20 mg,每晚1次,联合普罗布考片500 mg,2次/d,疗程6个月。对照组选取34例患者给予口服立普妥片20 mg,每晚1次,疗程6个月,观察治疗前后颈动脉内膜粥样硬化斑块变化的情况。结果:治疗前两组性别、年龄、颈动脉内膜的动脉粥样硬化斑块长度、厚度等方面比较差异无统计学意义(P>0.05),两组治疗后TC、TG明显降低,颈动脉内膜粥样硬化斑块明显缩小,差异有统计学意义(P<0.05)。结论:立普妥片联合普罗布考片治疗颈动脉粥样硬化斑块显著,可降低胆固醇水平,缩小颈动脉内膜粥样硬化斑块。
作者 李欣 程宏
出处 《吉林医学》 CAS 2015年第3期416-417,共2页 Jilin Medical Journal
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