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猪圆环病毒2型复制与转录模式研究进展

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摘要 猪圆环病毒是一种单股负链环状DNA病毒,有PCV1和PCV2两种血清型,PCV1一般认为无致病性,而PCV2是导致断奶仔猪多系统衰竭综合症的重要病原,给养猪业造成了巨大的经济损失。PCV复制模式为坩埚滚环复制,须依赖于Rep和Rep,蛋白的共表达、病毒复制起始区和双链DNA片段的形成,三者缺一不可;其转录模式也较为复杂,可双向进行且通过选择性剪切从而产生不同的RNA。主要对PCV2复制模式和转录模式等方面进行综述,以期为PCV的相关研究提供借鉴和参考。
出处 《猪业科学》 2015年第1期106-107,共2页 Swine Industry Science
基金 "携带遗传标记的猪圆环病毒反向遗传操作平台的构建"[黔科合LH字(2014)7670] 贵州省农业科技攻关项目"贵州省规模化猪场猪繁殖障碍性疫病防控体系的研究与示范"[黔科NY(2010)3042]
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参考文献8

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