期刊文献+

宫颈糜烂患者中TCT正常者HPV感染状况探讨 被引量:1

下载PDF
导出
摘要 目的探讨宫颈糜烂患者中超薄液基细胞学检测(TCT)结果正常者人乳头瘤状病毒(HPV)的感染状况。方法 316例宫颈糜烂且TCT检测结果均正常的患者,采用基因扩增和导流杂交技术,进行HPV基因分型检测,分析该群体中HPV的感染率及病毒分型状况。结果该群体中HPV感染者96例(感染率为30.4%),重度糜烂比轻度糜烂感染率高(P<0.05),以单一病毒亚型感染为主,感染率最高的为16亚型;多重感染者中,感染率最高的为18与53亚型。结论尽管宫颈糜烂患者TCT正常,但HPV的感染率仍然较高,因此对宫颈糜烂患者实施HPV检测,将有利于对宫颈癌高危人群的筛查与监测。
出处 《中国实用医药》 2014年第36期59-60,共2页 China Practical Medicine
  • 相关文献

参考文献3

二级参考文献23

  • 1李淑敏,章文华,吴令英,赵芳辉,黄曼妮,李楠,陈凤.人乳头状瘤病毒负荷量与子宫颈癌及其癌前病变关系的初步研究[J].中华妇产科杂志,2004,39(6):400-402. 被引量:76
  • 2[1]Zur Hausen H.Papillomaviruses and cancer:from basic studies to clinical application.Nat Rev Cancer,2002,2:342-350.
  • 3[2]Clifford GM,Smith JS,Plummer M,et al.Human papillomavirus types in invasive cervical cancer worldwide:a meta-analysis.Br J Cancer,2003,88:63-73.
  • 4[3]Munoz N,Bosch FX,Sanjose S,et al.Epidemiologic Classification of Human Papillomavirus Types Associated with Cervical Cancer.N Engl J Med,2003,348:518-527.
  • 5[4]Chan PK,Mak KH,Cheung JL.etal.Genotype spectrum of cervical human papillomavirus infection among sexually transmitted disease clinic patients in Hong Kong.J Med Virol,2002,68:273-277.
  • 6[5]Chan PK,Chang AR,Cheung JL,et al.Determinants d cervical human papillomavirus infection:differences between high-and low-oncogenic risk types.J Infect Dis,2002,185:28-35.
  • 7[7]Woodman CB,Collins S,Winter H,et al.Natural history of cervical human papillomavirus infection in young women:a longitudinal cohort study.Lancet,2001,357:1831-1836.
  • 8Schiffman M H,Brinton L A.The epidemiology of cervical carcinogenesis[J].Cancer,1995,76 (10 Suppl):1888-1901.
  • 9Zur Hausen H.Papillomaviruses causing cancer:evasion from host-cell control in early events in carcinogenesis[J].J Natl Cancer Inst,2000,92(9):690-698.
  • 10Dalstein V,Riethmuller D,Pretet J L,et al.Persistence and load of high-risk HPV are predictors for development of high-grade cervical lesions:a longitudinal French cohort study[J].Int J Cancer,2003,106(3):396-403.

共引文献75

同被引文献6

二级引证文献3

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部