参麦萸术饮治疗小儿支气管哮喘的效果观察

Effect observation of Shenmai Yuzhu decoction in the treatment of children with bronchial asthma

目的评价参麦萸术饮治疗小儿支气管哮喘的临床疗效及安全性。方法选取2012年5月-2013年4月本院收治的小儿支气管哮喘患者120例,随机分为观察组和对照组,其中对照组60例,采用抗生素等西医常规治疗,观察组60例,在对照组西医常规治疗的基础上加用中医辨证（参麦萸术饮）治疗,观察并比较两组患者临床疗效、肺功能指标及不良反应发生率。结果两组总有效率比较差异有统计学意义（P〈0.05）;两组治疗后的PEF、FEV1相比治疗前均有明显改善,差异有统计学意义（P〈0.05）;观察组治疗后的PEF及PEV1改善较对照组更明显,差异有统计学意义（P〈0.05）;两组患者治疗过程中均未出现腹痛、腹泻、恶心、呕吐、心慌及皮疹等不良反应。结论在抗生素等常规西医治疗的基础上加用参麦萸术饮治疗小儿支气管哮喘的临床疗效好,肺功能指标改善明显,无明显不良反应发生,值得临床推广。

Objective To evaluate clinical efficacy and safety of Shenmai Yuzhu decoction in the treatment of children with bronchial asthma. Methods 120 children with bronchial asthma from May 2012 to April 2013 in our hospital were selected and randomly divided into observation group and control group,antibiotics and other conventional western medicine treatment were used in control group（60 cases）,syndrome differentiation with TCM（Shenmai Yuzhu decoction）was applied in observation group（60 cases） based on the treatment of control group.Clinical curative effect,the index of lung function and adverse reaction of two groups were observed and compared. Results Total effective rate in two groups was compared,with statistical difference（P〈0.05）.PEF and FEV1 in two groups after treatment was improved than that before treatment respectively,with statistical difference（P〈0.05）.PEF and FEV1 in observation group after treatment was improved than that in control group respectively,with statistical difference（P〈0.05）.Two groups of patients during treatment had no adverse reactions of abdominal pain,diarrhea,nausea,vomiting, lustered and rash. Conclusion Shenmai Yuzhu decoction in the treatment of children with bronchial asthma on the basis of antibiotics and other conventional western medicine therapy has good effect,pulmonary function index is improved significantly,without obvious adverse reaction,and is worthy of clinical promotion.