青岛市开发区居民血脂调查分析

Investigation and analysis of blood lipid on development area residents in Qingdao City

目的了解青岛市开发区居民血脂情况,分析其与心脑血管疾病的相关性,指导沿海城市居民的饮食及生活习惯。方法采用整群随机抽样方法 ,收集2014年1-6月来本院心内科门诊就诊的患者和陪人共1606例,按是否患有冠心病、高血压、糖尿病、脑卒中分为正常人群组和异常人群组;按年龄分为35-50岁、〉50岁组;按性别分为男女两组。所有调查对象均进行血脂测定,根据《中国成人血脂异常防治指南（2007年）》对血脂情况进行判断,并比较各组别之间的差异,总结其相关规律性。结果被调查人群总胆固醇（TC）为（4.82±1.01）mmol/L,三酰甘油（TG）为（1.56±0.77）mmol/L,低密度脂蛋白-胆固醇（LDL-C）为（2.75±0.95）mmol/L,高密度脂蛋白-胆固醇（HDL-C）为（1.37±0.41）mmol/L。血脂异常率为66.6%。异常人群组的血脂指标值明显高于正常人群组的血脂指标值,差异有统计学意义（P〈0.05）。TC、TG和LDL-C随年龄增长而增高,≤50岁男性明显高于女性,〉50岁则男性有年轻化趋势甚至低于女性。男性HDL-C水平始终低于女性,女性HDL-C水平基本稳定不变。结论沿海城市居民具有较高的血脂异常患病率,且血脂代谢水平与多种因素相关,其中与各种心脑血管疾病最为密切。

Objective To know the blood lipid conditions on development area residents in Qingdao,and analyze the correlation between blood lipid and cardiovascular and cerebrovascular diseases in order to provide guidance for coastal city residents on their dietary habit and life style. Methods By cluster random sampling,from January to June in2014,1606 participants including patients and those who accompanied with them in our outpatient clinic in Department of Cardiology were selected.Based on whether they suffered from coronary heart disease,hypertension,diabetes mellitus,and cerebral apoplexy,and were divided into normal group and abnormal group.From age,they were divided into two groups： group aged from 35 to 50 years old and group over 50 years old.From gender,they were divided into male and female.Blood lipid in all participants was tested.According to 2007 Chinese Guidelines on Prevention and Treatment of Dyslipidemia in Adults,the conditions of blood lipid in these participants were judged and the differences between each group were compared so as to summarize the related regularities. Results The total cholesterol（TC）,triglyceride（TG）,low density lipoprotein-cholesterol（LDL-C）,and high density lipoprotein-cholesterol（HDL-C） among these investigated people was（4.82±1.01） mmol/L,（1.56±0.77） mmol/L,（2.75±0.95） mmol/L,and（1.37±0.41） mmol/L respectively.The rate of dyslipidemia was 66.6%.The value of blood lipid in the abnormal group was greatly higher than that in the normal group, with significant difference（P〈0.05）.With age increasing,TC,TG,and LDL-C also increased.Before 50 years old,the levels of these three indexes in male were much higher than those in female,but after 50 years old,the levels of these indexes had a trend to be younger,even lower than those in female.The level of HDL-C in male was always lower than that in female.The level of HDL-C in female basically kept stable. Conclusion Residents along coastal city display a higher rate of dyslipidemia.Blood lipid metabolism level is influenced by a variety of factors,among them cardiovascular and cerebrovascular diseases are closely related.