补肾活血法治疗强直性脊柱炎的理论基础

Theoretical basis of tonifying kidney and activating blood therapy for ankylosing spondylitis

强直性脊柱炎(AS)是一慢性难治性自身免疫性疾病,以附着点炎、骨破坏、异位成骨为主要病理表现。晚期易发生脊柱硬化强直,导致残疾。中医学中,AS属于痹症、大偻的范畴。综合经典以及众多医家的观点,可知:肾虚是该病发病的根本原因,血瘀贯穿该病始终,肾虚血瘀证是该病的基本证候,补肾活血是治疗该病的基本方法之一。肾虚血瘀也是AS骨质疏松、骨破坏的发病关键,补肾活血是防治AS骨破坏的重要手段。

Ankylosing spondylitis,a kind of chronic autoimmune disease,is characterized as enthesitis,osteoclasia and ectopic bone formation. If there＇s no good therapy,it would progress and cause ankylosis,which will infect patients＇ life severely. In traditional Chinese medicine（ TCM）,it＇s called Bi syndrome or ＂Dalv＂in Chinese spelling. In this article,ancient classics and many experts＇ opinions would be discussed. According to the TCM theories,deficiency of kidney is the basic cause; stasis of blood exists all through the disease. Pattern of kidney-deficiency and blood-stasis is a basic type of differentiation and the morbidity key of osteoporosis and bone destruction. Tonifying kidney and activating blood is the basic method for treating AS and also the important way to prevent and treat osteoclasia in AS.