凡纳滨对虾过敏原结构与性质的研究进展

Research Advances in Structure and Properties of Litopenaeus vannamei Allergens

凡纳滨对虾是一种营养价值高且具有致敏性的水产品,其引发的过敏反应逐渐引起研究者的重视。本文综述了凡纳滨对虾中4种分子质量在20~80 ku范围的过敏原蛋白（即原肌球蛋白、精氨酸激酶、肌球蛋白轻链以及肌浆结合蛋白）的性质、分子组成、空间结构及其各蛋白的致敏表位等诸多方面,这些将十分有益于更好了解这些过敏原蛋白的致敏机理以及降低过敏原性。

Litopenaeus vannamei has been widely used in the food industry due to its excellent nutritional value and delicious taste, but unfortunately, consumption of Litopenaeus vannamei can cause allergic reactions in some people. Therefore, it has gained growing attention from many researchers. In this paper, the properties, composition, spatial structure, and allergic epitopes of four kinds of allergens including tropomyosin （TM）, arginine kinase （AK）, myosin light chain （MLC） and sarcoplasmic calcium-binding protein （SCP） with molecular weights between 20 and 80 ku are reviewed. This paper will be useful for a better understanding of the mechanisms of these allergenic proteins and reduction of their allergenicity.