去氧孕烯炔雌醇片治疗青春期功能性子宫出血临床观察

Desogestrel and Ethinylestradiol Tablets Clinical Observation on the Treatment of Adolescent Dysfunctional Uterine Bleeding

目的探讨去氧孕烯炔雌醇片治疗青春期功能性子宫出血的临床疗效。方法将我院收治的72例青春期功能性子宫出血患者随机分成实验组与对照组两组,每组各36例,实验组患者采用去氧孕烯炔雌醇片进行治疗,对照组患者采用结合雌激素片进行治疗。比较分析两组临床疗效与不良反应发生情况。结果实验组患者的总有效率是94.44%,对照组患者的总有效率是75.00%,实验组的总有效率明显高于对照组,两组之间的差异具有统计学意义(P<0.05);实验组患者的控制出血时间、完全止血时间均明显少于对照组,两组之间的差异具有统计学意义(P<0.01);实验组患者的不良反应发生率为11.11%,对照组患者的不良反应发生率为30.56%,实验组的不良反应发生率明显小于对照组,两组之间的差异具有统计学意义(P<0.05)。结论采用去氧孕烯炔雌醇片治疗青春期功能性子宫出血的临床疗效显著,止血效果好,安全性较高。

Objective To investigate the therapeutic effect of Desogestrel and Ethinylestradiol Tablets treatment of puberty dysfunctional uterine bleeding clinical curative effect. Methods 72 cases of adolescent dysfunctional uterine bleeding in our hospital were randomly divided into an experimental group and a control group, each group has 36 cases, the experimental group were treated with Desogestrel and Ethinylestradiol Tablets treatment, patients in control group were treated with premarin. The clinical efifcacy and adverse reactions of the two groups were analyzed and compared. Results The total effectiveness of the experimental group is 94.44%, while the control group is75%, the total effective rate of the experimental group was significantly higher than that of the control group,（P 〈 0.05）, the controlled time of bleeding and complete hemostasis time in the experimental group were signiifcantly less than the control group, （P〈 0.01）, the adverse reaction rateof the patients in the experimental group was 11.11%, while in the control group the rate was 30.56%, which was significantly higher than that of experimental group, （P 〈 0.05）. Conclusion Desogestrel and Ethinylestradiol Tablets in the treatment of adolescent dysfunctional uterine bleeding have remarkable clinical curative effect, good hemostatic effect and high safety,which is worthy of clinical popularization and application.