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血栓与出血 被引量:5

Thrombosis and bleeding
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摘要 经皮冠状动脉介入治疗与抗栓药物在显著降低急性冠状动脉综合征患者缺血事件的同时,也相应增加了出血风险。出血发生率增高与患者不良临床预后强烈相关。全面评估患者出血风险进行危险分层,谨慎平衡缺血与出血风险制定治疗策略,预防控制出血并发症,在临床实践中非常重要。 Percutaneous coronary intervention and antithrombotic therapy have resulted in significant improvement in reducing ischemic events in acute coronary syndrome(ACS), at the same time leading to an increase in the risk of bleeding. There has been increasing data demonstrating that bleeding has a strong association with subsequent adverse outcomes. Therefore, it is imperative to optimize patient outcomes by performing bleeding risk assessment and stratification, adopting pharmacological and nonpharmacological strategies to minimize bleeding while maximizing treatment efficacy.
出处 《中国实用内科杂志》 CAS CSCD 北大核心 2015年第1期18-23,共6页 Chinese Journal of Practical Internal Medicine
关键词 抗栓治疗 血栓 出血 antithrombotic therapy thrombosis bleeding
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  • 1Joseph Broderick,Sander Connolly,Edward Feldmann,Daniel Hanley,Carlos Kase,Derk Krieger,Marc Mayberg,Lewis Morgenstern,Christopher S. Ogilvy,Paul Vespa,Mario Zuccarello,王玉洁(译),刘娟(译),白璇(译),李新辉,孙虹(译),姚志成(译),张慧(译),牛英翔(译).成人自发性脑出血处理指南——2007年更新版:美国心脏协会/美国卒中协会卒中委员会、高血压研究委员会、医疗质量和转归研究跨学科工作组指南:美国神经病学学会确认本指南作为神经科医生教学工具的价值[J].国际脑血管病杂志,2007,15(7):484-504. 被引量:235
  • 2GURBEL P A, BLIDEN K P, DICHIARA J, et al. Evalu- ation of dose-related effects of aspirin on platelet function: results from the Aspirin-Induced Platelet Effect (ASPECT) study[J]. Circulation, 2007, 115(25): 3156-3164.
  • 3GOROG D A, SWEENY J M, FUSTER V. Antiplatelet drug ' resistance '. Part 2: laboratory resistance to antiplatelet drugs-fact or artifact? [J]. Nat Rev Cardiol, 2009, 6(5): 365-373.
  • 4SARAF S, CHRISTOPOULOS C, SALHA I B, et al. Impaired endogenous thrombolysis in acute coronary syn- drome patients predicts cardiovascular death and nonfatal myocardial infarction[J]. J Am Coll Cardiol, 2010, 55(19) : 2107-2115.
  • 5BARK D L Jr, KU D N. Wall shear over high degree stenoses pertinent to atherothrombosis [J]. J Biomech, 2010, 43(15): 2970-2977.
  • 6WIVIOTT S D, BRAUNWALD E, MCCABE C H, et al. Prasugrel versus clopidogrel in patients with acute coronary syndromes[J]. NEnglJ Med, 2007, 357(20): 2001-2015.
  • 7MONTALESCOT G, WIVIOTT S D, BRAUNWALD E, et al. Prasugrel compared with clopidogrel in patients under- going percutaneous coronary intervention for ST-elevation myocardial infarction (TRITON-TIMI 38) : double-blind, randomised controlled trial[J]. Lancet, 2009, 373(9665) 723-731.
  • 8GURBEL P A, BLIDEN K P, BUTLER K, et al. Response to ticagrelor in clopidogrel nonresponders and responders and effect of switching therapies: the RESPOND study [J]. Circulation, 2010, 121(10): 1188-1199.
  • 9The Medicines Company. The Medicines Company discon- tinues phase 3 CHAMPION clinical trial program of cangrelor [EB/OL]. May 13, 2009. http://ir, themedici- nescompany, corn/phoenix, zhtml? c = 122204&-P = irol- newsArticle&ID = 1287788&highlight =. Accessed November 7. 20] 1.
  • 10RAO S. A randomized, double-blind, active controlled trial to evaluate intravenous and oral PRT060128 (elinogrel), a selective and reversible P2Y12 receptor inhibitor, vs clopidogrel, as a novel antiplatelet therapy in patients under- going non- urgent percutaneous coronary interventions (INNOVATE-PCI) [C]. European Society of Cardiology Congress,Stockholm, Augus 28-September 1, 2010.

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