自身炎症性疾病临床诊断

Clinical diagnosis of autoinflammatory disease.

自身炎症性疾病(autoinflammatory diseases or disorders,AIDs)是一组以反复发热、急性关节炎和急性期蛋白增加为特征的复发性非侵袭性炎症性疾病。以往由于认识不足以及缺乏诊断条件,对这类疾病估计不足。随着基因诊断技术的进步、炎症发生发展机制与信号通路研究的日益进展,近年来对自身炎症性疾病的研究有了飞速进展,这也对临床诊断提出了更新的挑战。

Autoinflammatory diseases or disorders（AIDs）area group of recurrent non-invasive inflammatory diseases characterized by fever,acute arthritis and elevated acute-phaseproteins. The disease was underestimated in large part duringthe past few years due to insufficient understanding and lackof means of diagnosis. With the increasing advance of geneticdiagnosis technology and of research on the mechanism of theinflammatory occurrence and the development and the signalpathway,study about the AIDs has made a rapid progress,which also proposed the new challenge to immunological pediatrician for clinical practice.