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儿童EB病毒相关性肾脏损伤临床特点分析 被引量:8

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摘要 目的总结分析儿童EB病毒(EBV)感染引起的肾脏损伤的临床特点。方法回顾性分析2008年1月至2013年12月在湖南省儿童医院肾内科住院诊断为EBV感染患儿617例临床资料。分析其肾脏损伤发生情况、感染严重程度及EBV复制水平与肾脏损伤间关系。结果 617例中肾脏损伤170例(27.6%)。其中单纯镜下血尿者22例(3.5%),单纯蛋白尿136例(22.0%),血尿+蛋白尿12例(1.9%),没有发现肉眼血尿及急性肾损伤者。617例中临床表现为传染性单核细胞增多症524例,其中单纯镜下血尿16例(3%),单纯蛋白尿116例(22.1%),血尿+蛋白尿10例(1.9%);临床表现为非特异性呼吸道感染症状93例,其中单纯镜下血尿6例(6.4%),单纯蛋白尿20例(21.5%),血尿+蛋白尿2例(2.1%)。进一步分析显示,感染严重程度与EBV复制水平、肾损伤发生间差异无统计学意义(P>0.05)。结论 EBV引起肾脏损伤的发生率较高,以单纯蛋白尿居多。其引起肾脏损伤发生情况与感染严重程度及EBV复制水平间差异无统计学意义。
出处 《中国实用儿科杂志》 CSCD 北大核心 2015年第1期71-73,共3页 Chinese Journal of Practical Pediatrics
基金 湖南省自然科学基金资助项目(11JJ3101) 湖南省高层次卫生人才"225"工程资助
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参考文献8

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