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核转录因子STAT3及其在结直肠癌中的应用价值 被引量:4

Application of Nuclear Transcription Factor STAT3 in Colorectal Cancer
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摘要 结直肠癌是全世界最常见的恶性肿瘤之一,也是我国大中城市发病率排名高居第二、三位的恶性肿瘤,且其近年来发病率呈上升趋势,严重地威胁了人们的健康和生命,现已采取了手术及放化疗等一系列综合治疗,但其治疗效果仍有待提高[1]。从分子水平上研究结直肠癌的发生、发展和转移,已成为目前结直肠癌研究的热点。信号传导及转录激活因子3(signal transducers and activators of tran-scription,STAT3)是STATs家族中的一员.
出处 《中国医科大学学报》 CAS CSCD 北大核心 2015年第1期1-4,9,共5页 Journal of China Medical University
关键词 STAT3 结直肠癌 治疗 转移与预后 TAT3 colorectal cancer treatment metastasis and prognosis
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