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艰难梭菌感染1例 被引量：1

One case report of Clostridium difficile infection
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摘要 1临床资料 患者男,75岁。2013年9月5日因“胰腺癌”收入我院肝胆外科,于9月12日行“胰十二指肠切除术”,术程顺利。2013年9月16日—10月1日患者间歇发热,体温波动于36.8-37.8℃。9月16日体格检查,心肺未见明显异常,腹平,切口愈合良好,发热原因待查。
作者 王洁 杨靖 赵建宏 田甜甜 强翠欣 李志荣
机构地区 河北医科大学第二医院检验科微生物室
出处 《中国感染与化疗杂志》 CAS CSCD 北大核心 2015年第1期76-77,共2页 Chinese Journal of Infection and Chemotherapy
基金 河北省自然科学基金(2013206450) 河北省科技厅基础条件平台建设项目(10966142D) 河北医科大学第二医院科研基金(2H0201011)
关键词 艰难梭菌 感染 腹泻
分类号 R378.8 [医药卫生—病原生物学]
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参考文献7

  • 1Surawicz CM, Brandt LJ, Binion DG, et al. Guidelines for diagnosis, treatment, and prevention of Clostridium diffici& infections[J]. Am J Gastroenterol, 2013,108 (4) 478 498.
  • 2Loo VG, Bourgault AM, Poirier I., et al. Host and pathogen factors for CZostridium difficile infection and colonization [J]. NEnglJ Med, 2011,365(18) :5693 1703.
  • 3Surawicz CM, Alexander J. Treatment of refractory and recurrent Clostridium difficile infection [J]. Nat Rev Gastroenterol Hepatol,2011,8(6) :330-339.
  • 4Hensgens MP, Goorhuis A, Dekkers OM, et al. Time interval of increased risk for CZostridium difficile infection after exposure to antibiotics[J]. J Antimicrob Chemother, 2012, 67(3) :742 748.
  • 5Dubberke ER, Reske KA, Yan Y, et al. Clostridium diJyicile- associated disease in a setting of endemicity: identification of novel risk factors[J]. Clin Infect Dis, 2007, 45(12) : 1543- 1549.
  • 6Currie BP, Lemos Filho L. Evidence for biliary excretion of vancomycin into stool during intravenous therapy: potential implications for rectal colonization with vancomycin resistant enterococci[J]. Antimicrob Agents Chemother, 2004, 48 (11) :4427-4429.
  • 7Dial S, Alrasadi K, Manoukian C, et al. Risk of Clostridium difficile diarrhea among hospital inpatients prescribed proton pump inhibitors: cohort and case control studies[J]. CMAJ, 2004,171(1) :33-38.

同被引文献10

  • 1Coia JE. What is the role of antimicrobial resistance in the new epidemic of CIostridiun difficile [ J ]. Int I Antimicrob Agents, 2009, 33 ( Suppl 1 ) : S9-12. DOI: 10. 1016/S0924-8579 (09) 70009-3.
  • 2Surawicz CM, Alexander J. Treatment of refraeto and recurrent Clostridium dificile infection[ J]. Nat Rev Gastroenterol Hepatol, 2011, 8(6) : 330-339. DOI: 10. 1038/nrgastro. 2011.59.
  • 3Lihua Z1, Danfeng D, Cen J, et al. Clinical eharacterization and risk factors of Clostridiurn diJficile infection in elderly palients in a Chinese hospital[J]. J Infect Dev Ctries,2015, 9(4) : 381-387. DOI: 10. 3855/jide. 4816.
  • 4Clinical and Laboratory Standards Institute. Methods for Antimicrobial Susceptibility Testing of Anaerobic Bacteria [ S ] Approved Standard: M l l-A7. Wayne,PA :CLSI, 2010.
  • 5Zheng L,Keller SF,Lyerly DM,et al. Muhicenter evaluation of a new screening test 1hat detects Clostridium difficile in fecal specimens [ J ]. J Clin Microbiol, 2004, 42 ( 8 ) : 3837-3840. DOI: 10. 1128/JCM. 42. 8. 3837-3840. 2004.
  • 6Epstein L, Golan Y. Fidaxmiei, a new treatment for C[ostridittm diflcile infections[J]. Drugs Today(Barc) , 2012, 48(2) : 101- 108. DOI: 10. 1358/dot. 2012.48.21746740.
  • 7Liao CH, Ko WC, Lu JJ, et al. Characterizations of clinical isolates of Clostridium difficile by toxin genotypes and by susceptibility to 12 antimicrobial agents, including fidaxomicin ( OPT-80 ) and rifaximin : a multicenter study in Taiwan [ J ]. Antimicrob Agents Chemother, 2012, 56 ( 7 ) : 3943-3949. OOl: 10. 1128/ AAC. 00191-12.
  • 8Lachowicz D, Pituch H, Obuch-Woszczatyfiski P. Antimicrobial susceptibility patterns of Clostridium difficile strains belonging to different polymerase chain reaction ribotypes isolated in Poland in 2012 [ J ]. Anaerobe, 2015, 31: 37-41. DOI: 10. 1016/ j. anaerobe. 2014.09. 004.
  • 9Kuwata Y,Tanimoto S, Sawabe E, et al. Molecular epidemiology and antinficrobial susceptibility of Clostridium diJftcile isolated from a university teaching hospital in Japan [ J ]. Eur J Clin Microbiol Infect Dis, 2015, 34(4) : 763-772. DOI: 10. 1007/ s10096-.014-2290-9.
  • 10杨靖,李志荣,赵建宏,强翠欣,李宏,温海楠,时东彦,李继红,宋文杰,魏宏莲,孙倩,李雅静,王洁.33株艰难梭菌临床分离株的多位点序列分型[J].中华检验医学杂志,2013,36(10):920-925. 被引量：13

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中国感染与化疗杂志
2015年 第1期

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