20例成人败血症临床分析

20 case adults sepsis clinical analysis

目的：分析本科室成人败血症的临床特点、病原体、治疗及转归。方法：回顾性分析本科室2010-2013年20例败血症患者的临床资料。结果：20例患者平均年龄为60．8岁，临床症状以畏寒发热为主（95％），白细胞计数（50％）及中性粒细胞比例（85％）升高。20例确诊为败血症患者血培养（18例）阳性或骨髓培养（2例）阳性，其中病原菌以大肠杆菌居多（40％），耐药率低，预后良好。结论：老年患者出现畏寒发热、白细胞升高等，应尽快进行血培养及骨髓培养，选用敏感抗生素，注意防治并发症，提高治愈率。

Objective ： To analyze clinical features, pathogens, treatments and outcomes with sepsis. Methods ： Clinical materials of 20 patients with sepsis in our department from 2010 to 2013 were analyzed by a case retrospective analysis.Results ： The mean age of these cases was 60.8, and most cases featured with fever and chi11（95%）, with leucocytes and neutrophilic percentage increasing. Blood culture or bone marrow culture of all 20 cases was positive, and escherichia coli dominated（40%）, with lower rate of drug-resistant and better outcomes. Conclusions ： Blood culture and bone marrow culture should be applied as soon as possible in old patients with chill, fever and high white blood cell count. Use of appropriate antibiotics after diagnosis and prevention for complications were crucial for recovery rate.