血小板早期输注对重型再生障碍性贫血患者出血症状疗效观察

Hemorrhage symptoms curative effects observation of platelet early transfusion to patients with severe aplastic anemia

目的：探讨重型再生障碍性贫血（sAA）患者早期输注单采少白细胞血小板（PLT）对出血发生的改善和控制作用。方法：随机分为两组对比观察，观察组及对照组各24例，观察组患者早期输注PLT，并给予常规sAA治疗方案；对照组仅给予常规SAA治疗方案。采集患者输注PLT前后1h与24h静脉血，计算校正PLT计数增加指数及PLT回收率；两组出血症状改善情况。结果：经观察，sAA患者早期输注PLT后，观察组出血率为16．7％，对照组出血率为87．5％，两组有显著性差异（P〈0．05），观察组止血有效率明显高于对照组组。结论：SAA患者早期输注PLT明显降低出血风险，为临床治疗sAA提供了宝贵时间。

Objective ： To Discuss severe aplastic anemia （SAA） in patients with early transfusion of platelets （PLT） for the improvement and control of bleeding effect. Methods ： The patients were randomly divided into two groups, the observation group （n=24） and the control group （n=24）, the observation group of patients with early PLT infusion, were also given regular SAA treatment; The control group only were given regular SAA treatment plan. Before and after the infusion PLT lh and 24h the venous blood of all the patients were caUected. Calculate correction PLT count index and PLT recovery; Two groups of bleeding symptoms improve the situation.Results ： Through observation, SAA patients early after infusion PLT, observation group hemorrhage rate was 16.7%, the control hemorrhage rate was 87.5%, two groups have significant difference （P〈0.05）, hemostatic efficient observation group was obviously higher than that of control way. Conclusions ： Early transfusion PLT reduce the hemorrhage probability obviously, provides precious time for clinical treatment.