佛山地区女性生殖道无乳链球菌感染和耐药性分析

Women genital tract streptococcus agalactiae infection and drug resistance in Foshan area

目的：了解佛山地区非孕女性生殖道无乳链球菌的感染和耐药情况，为临床感染的预防和治疗提供科学依据。方法：收集本院非孕女性生殖道标本作无乳链球菌培养，采用法国梅里埃公司生产的ATB半自动细菌鉴定分析仪进行鉴定和药敏分析。结果：8891份标本共有122份检出无乳链球菌，检出率为1．37％。药敏结果显示对万古霉素全敏感，青霉素、氯霉素、四环素、红霉素、氯洁霉素、头孢噻肟、左氧氟沙星和喹奴普丁一达福耐药性分别为4．1％、15．6％、91．0％、59．8％、55．7％、1．6％、14．8％和7．4％。结论：本地区非孕女性生殖道无乳链球菌感染率总体较低，青霉素可作为治疗的首选药物。

Objective ： To study the infection and drug resistance status of streptococcus agalactiae from genital tract of women without pregnant and provide the basis for clinical prevention and treatment of infection. Methods ： Secretions specimens from genital tract of women without pregnant were collected. The identification and antimicrobial susceptibihty test of streptococcus agalactiae were determined by ATB system.Results ： A total of 8891 specimens were collected and the positive incidence of streptococcus agalactiae was 1.37%. The antimicrobial susceptibility tests showed all the isolates were sensitive to vancomycin, and the antimicrobial resistance rate of penicillin, chloramphenicol, tetracycline, erythrocin, clindamyein, cefotaxime, levofloxacin and quetiapine putin-dafoe was 4.1%, 15.6%, 91.0%, 59.8%, 55.7%, 1.6%, 14.8% and 7.4%, respectively. Conclusions ： The infection rates of streptococcus agalactiae in women without pregnant is not high, and penicillin can be used as a first-choice treatment for streptococcus agalactiae infections.