降钙素原在尿路感染中的诊断价值研究

Diagnostic value of procalcitonin in urinary tract infection

目的 评价降钙素原在尿路感染诊断中的价值.方法 收集2012年9月～2013年10月入住本院泌尿外科疑似尿路感染的患者114例,进行血清降钙素原（PCT）及中断尿培养检测,其中尿培养阳性的46例作为观察组,尿培养阴性的71例作为对照组,分析两组患者PCT水平差异,并通过ROC曲线得出诊断二者的临界点.结果 尿路感染组患者PCT水平为11.32±27.14ng/mL,高于非尿路感染组患者的PCT水平（0.75±2.00ng/mL）,两组差异具有统计学意义（P＜0.05）.以PCT0.2ng/mL为诊断临界点预测尿路感染的敏感度为91.3％,特异度为62％.结论 PCT检测快速,干扰因素少,应用于尿路感染的诊断具有诊断价值.

Objectives To evaluate the value of procalcitonin in the diagnosis of urinary tract infection （UTI）.Methods From 2012.9.1 to 2013.10.31,a total of 114 patients suspected of urinary tract infection were collected and serum procalcitonin and urine culture were detected.46 patients with positive urine culture were set as observation group.the 71 negetive cases were set as control.The procalcitonin levels of the two groups were analyzed.The cut-off of the two groups was finded by using the receiver operating characteristic （ROC） curve.Results The PCT level of the observation group was 11.32 ± 27.14ng/ml and higher than the control（0.75 ± 2.00ng/ml）.The difference between the two group was significant （P 〈 0.05）.The cut-off of PCT was 0.2ng/ml,the sensitivity and specificity were 91.3% and 62% respectively.Conclusions The detection of PCT is fast and has less interference factors.PCT is valuable in the diagnosis of UTI.