干扰素γ临床应用新进展

Progress in the clinical application of interferon gamma

干扰素γ（IFN-γ）属于Ⅱ型干扰素，是一种具有抗肿瘤，抗病毒，免疫调节等生物学功能的细胞因子，已经应用于医学研究和临床多种疾病的治疗。近年来，IFN-γ在抗肿瘤，抗感染和治疗自身免疫病方面有了更广泛的应用，然而也有报道称IFN-γ可以促进某些疾病的发生。因此分析总结IFN-γ在一些疾病中的作用机制及作用效果，对于临床应用具有重要的指导意义。

Interferon gamma（IFN-γ） ,belonging to type II interferon,is a kind of cytokine with antitu- mot, antiviral,immune regulatory as well as other biological effects. IFN-γ has been applied to medical research and clinical treatment for various diseases. In recent years, IFN-γ has wide applications in antitumor, anti-infec- tion and the treatment of autoimmune diseases. However,it has also been reported that IFN-γ may promote the oecurance of certain diseases. Therefore, we summarized the recent reports and expectation of IFN-γ in the clinical application.