尖锐湿疣合并感染其他性病的临床研究

Clinical study on joint infection of genital warts and other sexually transmitted diseases

目的:对尖锐湿疣发病与其他性传播疾病的关系展开研究分析,旨在为临床治疗尖锐湿疣提供有利依据。方法:随机选取2011年3月至2013年3月期间我院接收救治的400例尖锐湿疣患者,分成男性组和女性组各200例。对两组淋球菌、沙眼衣原体以及解脲支原体等进行检测对比,并对两组于中西医结合主动免疫基础上给予光动力疗法治疗,对其治疗后临床疗效进行观察对比。结果:两组400例患者经过临床检测研究后,对其病原体检测结果进行观察对比。男性组患者合并其他性病总感染率34.0%,女性组患者合并其他性病总感染率56.0%,男性组总感染率显著低于女性组,数据差异具有统计学意义(P<0.05);两组患者合并解脲支原体感染16.0%、26.0%,显著高于淋球菌感染10.0%、16.0%,显著高于沙眼衣原体感染8.0%、14.0%,数据差异具有统计学意义(P均<0.05);两组400例患者于中西医结合主动免疫基础上给予光动力疗法治疗后,对其临床疗效进行观察对比。其中合并其他性病病原体感染的患者治愈情况为男性组总有效率95.5%,女性组总有效率94.6%,比较男女患者间数据无显著差异(P>0.05)。单一HPV感染者治愈情况为男性组有效率94.7%,女性组有效率94.3%,比较男女患者间数据无显著差异(P>0.05)。同时合并其他性病病原体患者与单一HPV感染患者间数据也无显著差异(P>0.05)。结论:尖锐湿疣复发受尖锐湿疣合并其他性病感染重要影响,临床治疗尖锐湿疣患者通过对患者其他性病病原体进行有效检测,并及时对合并其他感染的患者开展治疗,临床疗效显著。

Objectives：To research and analyze the relationships between genital warts and other sexually transmitted diseases,to provide a favorable basis for the clinical treatment of genital warts.Methods：400 patients with genital warts received treatment in our hospital from March 201 1 to March 2013 were selected and randomly di-vided into male and female group,each of 200 cases.The nisei gonorrhea,chlamydia trachoma and mycoplasma urealytium of the two groups were detected and compared,and both groups received active immunization and photo-dynamic therapy on the basis of integrated traditional Chinese and western medicine.The clinical efficacy was com-pared.Results：The pathogen detection results of the two groups were observed and compared.The overall infection rate of male group and female group was 34.0% and 56.0% respectively,with statistically significant difference （P〈0.05）;the incidences of joint infection with mycoplasma urealytium of the two groups were 16.0%,26.0%, significantly higher than these of gonococci infection （10.0%,16.0%）and Chlamydia （8.0%,14.0%）,with sta-tistically significant differences （P 〈0.05 ）.The clinical efficacy of both groups after having received active immu-nization and photodynamic therapy on the basis of integrated traditional Chinese and western medicine was observed and compared.The total cure rate for joint infection with sexually transmitted diseases of male and female group was 95.5% and 94.6% respectively,with no significant difference （P〉0.05）.The cure rate of single HPV infection of male and female group was 94.7% and 94.3% respectively,without significant difference （P〉0.05）.There was also no significant difference between data of patients with joint infection of other sexually transmitted diseases and single HPV infection （P〉0.05 ）.Conclusion：Infection of other sexually transmitted diseases associated with genital warts has a significant impact on the recurrence of genital warts.Detection and timely treatment of other sex-ually transmitted diseases is of significant clinical effect in treating patients with genital warts.