软组织恶性纤维组织细胞瘤超声及病理特征

Ultrasonographic and pathological features of soft tissue malignant fibrous histiocytoma

目的探讨软组织恶性纤维组织细胞瘤(MFH)的超声及病理特征。方法分析11例MFH的超声和病理特点。结果 MFH超声表现以低回声为主,有包膜,与周围组织分界清晰,后方回声稍增强,周边及内部均可见血流信号。组织学呈明显多形性,免疫组化主要表达波形蛋白(Vim)和巨噬细胞(CD68)。结论 MFH是一种起源于间叶组织的恶性肿瘤,中老年多见,多发生于深层软组织,无明显临床特征,超声对MFH的诊断有重要价值,确诊需要依靠病理检查。

Objective To investigate the ultrasonogphic and pathological features of malignant fibrous histiotoma. Methods The ultrasonogphic and pathological features of eleven cases of malignant fibrous histiotoma were analysed retrospectively. Results MFH mainly presented hypoecho, had envelope and clear boundary with surrounding tissue, showed posterior enhancement and both peripheral and internal blood flow signal.Histological findings showed obvious polymorphism, immunohistochemical results mainly found vimentin （Vim） and macrophages （CD68） expression. Conclusion Ultrasonography can be very helpful for the diagnosis of malignant fibrous histiotoma,but it still relies on pathology to make a definite diagnosis.