一种计算手术中七氟烷消耗量的简便方法

A simple method to calculate the consumption of sevoflurane during surgery

目的设计一种简便的七氟烷用量计算方法,并与称重法以及公式计算法结果进行比较,验证该方法的可行性。方法试验一,将七氟烷加入挥发罐至基线水平后,采用注射器加药,同时采用直尺测量,记录每次加药后液面升高1mm距离所需要的七氟烷液体量,加药至最高标志线。试验二,选择全身麻醉下行妇科腹腔镜手术的患者25例,麻醉维持采用静吸复合麻醉,麻醉医师通过调节新鲜气流量以及挥发罐刻度来调整麻醉深度。分别以测量法、称重法以及公式法计算手术中吸入麻醉药的用量。结果称重法与公式法计算七氟烷消耗量的相关系数R2为0.9295(P<0.001);称重法与测量法计算七氟烷消耗量的相关系数R2为0.9778(P<0.001)。结论采用测量法计算手术中七氟烷用量简便易行,结果可靠。

Objective To design and verify a simple method to calculate the consumption of sevoflurane during surgery, by comparing it with weighting method and formula method. Methods In experiment part one, sevoflurane was added into vaporizer by using an injection syringe from the mini volume line. Straightedge was used to verify how much sevoflurane would elevate one millimeter in the height of liquid level line,and sevoflurane was added until the liquid reached the maximum volume line. In experiment part two,twenty-five female patients undergoing gynecological laparoscopic surgery, ASA I-U, were randomly allocated to receive intravenous inhalational anesthesia after intravenous anesthesia induction. The anesthesiologist adjust the depth of anesthesia by regulating the fresh gas flow and vaporizer dial. Weighting method, measurement method and formula method were adopted to calculate the consumption of sevoflurane during surgery. Results The Spearman＇s correlation coefficient （R2） between formula method and weighting method was found to be 0. 9295 and was highly statistically significant （P 〈0. 001 ）. The correlation between measurement method and weighting method was statistically significant and the correlation coefficient R2 was 0. 9778 （P〈0. 001 ）. Conclusions Measurement method is a simple and reliable method to calculate the consumption of sevoflurane during surgery.