ISCD和IOF关于骨质疏松骨折风险评估(FRAX)临床应用的共识

Concensus of the clinical use of FRAX by International Society for Clinical Densitometry and International Osteoporosis Foundation

国际临床骨密度学会(International Society for Clinical Densitometry,ISCD)和国际骨质疏松基金会(International Osteoporosis Foundation,IOF)于2010年11月14日在罗马尼亚的Bucharest召开FRAX共识会议(PDC),随后召开了为时两天的主题为"FRAX在临床应用的共识"的ISCD和IOF共同会议。在来自ISCD和IOF的国际专家组和FRAX专项专家的带领下,这3天关键性的探讨和辩论阐明了很多关于FRAX在临床应用中的重要内容。PDC形成的官方共识目的在于在全世界范围内提高FRAX的临床应用质量和效能。由于骨骼评估是一个全新的并且发展迅速的领域,在PDC上发表的一些临床上十分重要的内容尚无确凿的医学证据。因此,一些官方共识很大程度上基于专家的意见。尽管任何发展进程中都会像这样存在一定局限,但ISCD和IOF相信,为临床医师和技术人员提供目前骨密度测量学科知识的精华,以及为科学团队提供指引是否需要进行更深入的研究来解释未知的和/或正存在争议的领域是十分重要的。

The International Society for Clinical Densitometry （ ISCD ） and the International Osteoporosis Foundation （ IOF ） convened the Position Development Conference （PDC） in Bucharest, Romania, on November 14, 2010, following a two-day joint meeting of the ISCD and IOF on the“Interpretation and Use of FRAX in Clinical Practice”.These three days of critical discussion and debate, led by a panel of international experts from ISCD, IOF, and by dedicated task forces, have clarified a number of important issues pertaining to the interpretation and implementation of FRAX in clinical practice.The Official Positions resulting from the PDC are intended to enhance quality and clinical utility of fracture risk assessment worldwide.Since the field of skeletal assessment is new and evolving rapidly, some clinically important issues addressed at the PDCs are not associated with robust medical evidence.Accordingly, some Official Positions are based largely on expert opinion.Despite limitations inherent in any process such as this, ISCD and IOF believe that it is important to provide clinicians and technologists with the best distillation of current knowledge in the discipline of bone densitometry and to provide guidance to the scientific community on where further research is needed to resolve areas of ambiguity and/or ongoing controversy.