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1,5-脱水葡萄糖醇的临床应用及研究进展 被引量:4

Clinical application of 1,5-anhydroglucitol and the research progress
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摘要 1,5-脱水葡萄糖醇(1,5-AG)是体内的一种无生理活性的多元醇,其在肾小管内的重吸收过程可被葡萄糖竞争性抑制。当血糖水平超过肾糖阈时,血清1,5-AG水平将快速下降,利用此特性,1,5-AG可用以反映短时间内血糖波动情况。本篇综述整理了1,5-AG的特点,目前在临床上的研究进展,以及1,5-AG在临床应用中的优势和局限性。 1,5-Anhydroglucitol (1,5-AG) is a metabolically inert polyol that competes with glucose for reabsorption in the kidneys. The stable level of 1,5-AG is rapidly depleted as blood glucose levels exceed the renal threshold for glucosuria. Thus, 1,5-AG can be used as a validated marker of short-term glycemic control. This article reviewed the features and research progress of 1,5-AG and assessed its advantages as well as limitations as a glycemic marker in clinical practice.
出处 《中华老年多器官疾病杂志》 2014年第11期867-871,共5页 Chinese Journal of Multiple Organ Diseases in the Elderly
关键词 1 5-脱水葡萄糖醇 血糖管理 血糖波动 餐后血糖 1,5-anhydroglucitol glycemic control glycemic excursion postprandial glucose
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