OCT的光密度研究在眼科的应用

Application of optical density studies with optical coherence tomography in ophthalmology

光密度测量是一种通过结合计算机技术,将待测组织的图像信号转换成数字化格式,分析图像像素及计算后获得待测组织透射/反射光强度,从而达到客观分析组织特性的一种分析技术.光密度可根据测量仪器产生图像的维度而提供二维或三维的信息,立体、全面地体现组织内部微结构的变化,近年来在眼科影像中逐渐引起关注,已有研究表明其在眼科疾病诊断及随访中的应用价值.现结合国内外研究从光密度的定义、光密度在各领域的应用、光密度测量的优缺点、眼科领域中的光密度分析方法、光学相干断层扫描的光密度研究在眼科疾病中的应用5个方面进行综述.

Optical density （OD） analysis is a kind of technology that analyzes transmitted/reflective light intensity of target tissue to learn certain characters of tissue objectively by calculating pixel values of tissue image with the help of computer technology.OD can provide 2-dimensional or 3-dimensional information and embody tiny changes of tissue systematically.It has aroused attention gradually in ophthalmology imaging in recent years.Various studies had shown diagnositc and prognostic value of OD in ocular diseases.This paper reviewed the definition of OD,application of OD in various fields,advantages and disadvantages of OD,analysis method of OD and application of OD in ophthalmology.