血红蛋白变异体对不同糖化血红蛋白检测系统的干扰

Interference of hemoglobin variants on HbA1emeasuring systems

糖化血红蛋白检测干扰因素众多，血红蛋白变异体是其中一个重要因素，这些常见的血红蛋白变异体对各种糖化血红蛋白检测系统存在不同的干扰，造成糖化血红蛋白结果错误，或者结果正确但不能反映患者平均血糖水平，容易给临床诊断、疾病监测带来影响。（中华检验医学杂志，2014，37：890-892）

There are many factors which may interfere with HbA1e measurement. Hemoglobin variant is one of the most important factors. Different hemoglobin variants may interference with different HbA1e measuring systems, resulting in HbA1e analytic interference or clinically misleading because of the values do not reflect the true glucose levels. This may affect clinical dignosis and disease monitoring. （ Chin J Lab Med. 2014.37.890-892 ）