顺式阿曲库铵预注射联合无通气诱导在全麻剖宫产中的应用

The Application of cisatracurium pre-Injection combined with no ventilation during rapid sequence induction of general anesthesia in patients undergoing caesarean section

目的探讨顺式阿曲库铵预注射联合无通气快速诱导用于全麻剖宫产术的安全性和可行性。方法拟行全麻下剖宫产手术的产妇22例,诱导前给予1/8-1/10诱导剂量的顺式阿曲库铵预注射,面罩吸入纯氧3min后行静脉快速诱导,诱导期间不实施正压辅助通气,观察并记录诱导前后HR、Sp O2、BP的变化及诱导过程中呛咳、呕吐、返流、误吸发生率。结果 T0、T1、T2与T3各时点的Sp O2分别为(96.57±0.61)%、(98.78±0.42)%、(97.94±0.35)%和(99.63±0.14)%。诱导过程平稳,气管插管前后Sp O2无显著变化;诱导过程中无缺氧、呕吐、返流、误吸发生,且插管条件较为理想。结论对拟行全麻剖宫产的非困难气道产妇,采用顺式阿曲库铵预注射联合无通气快速诱导技术是安全、可行的。

Objective To investigate the safety and the feasibility of applying cisatracurium pre-injection combined with no ventilation during rapid sequence induction of anesthesia in patients undergoing caesarean section. Methods 22 pregnant women undergoing caesarean section under general anesthesia were pre-injected cisatracurium 0.02mg/kg and inhaled 100% oxygen via face mask for 3 min without positive-pressure ventilation before induction of anesthesia. HR,SpO2,BP,ECG were monitored be-fore,during and after the induction. The incidence of bucking,vomiting,regurgitation and aspiration were recorded. Results The SpO2 at T0、T1、T2 and T3 are（96.57±0.61）%,（98.78±0.42）%,（97.94±0.35）%和（99.63±0.14）%. There were no significant changes on SpO2 and no hypoxia, regurgitation and aspiration took place in any cases. The intubation was ideal. Conclusion The technique of applying cisatracurium pre-injection combined with no ventilation during rapid sequence induction of anesthesia on the patients undergoing caesarean section is safe and feasible.