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低剂量地塞米松防治多西紫杉醇不良反应的可行性探讨

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摘要 目的探讨低剂量地塞米松防治多西紫杉醇不良反应不良反应的临床效果及安全性。方法选取我院76例使用多西紫杉醇治疗的患者,随机分成研究组和对照组各38例。对照组给予地塞米松1次8mg,1日2次的治疗,而研究组给予地塞米松1次4.5mg,1日1次的治疗。对两组的治疗效果及不良反应进行分析比较。结果对照组治疗总有效率为73.7%,而研究组总有效率达94.7%,明显高于对照组,差异具有统计学意义(P<0.05)。治疗后患者的不良反应发生率也显著低于对照组,数据差异具有统计学意义(P<0.05)。结论在使用多西紫杉醇治疗的肿瘤患者中采用低剂量地塞米松防治不良反应的方案具有显著的效果,安全性高,值得临床推广及应用。
出处 《海峡药学》 2014年第12期263-264,共2页 Strait Pharmaceutical Journal
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