经皮球囊成形术治疗儿童先天性主动脉瓣狭窄近期疗效及体会

Experience of percutaneous balloon aortic valvutoplasty for congenital valvular aortic stenosis

主动脉瓣狭窄（AS）可由不同病因引起,其中先天性AS占先天性心脏病的3%-6%。自1984年Lababidi等首次报道经皮球囊主动脉瓣成形术（PBAV）治疗先天性AS至今30多年,该方法在西方逐步发展为可替代外科瓣膜切开,成为治疗儿童先天性AS的有效介入手段。由于我国AS的发病率较欧美国家低,且术中可能发生严重并发症,国内开展较少。

Summary A total of 9 children with aortic stenosis underwent PBAV. All patients were successfully completed PBAV. The ratios of balloon/valve were 0.8--1.1 （0.97±0.11）. The peak aortic valve gradients decreased from （89.9±14.4） mmHg（1 mmHg=0. 133 kPa） pre-PBAV to （43.6±24.8）mmHg immediately after PBAV（P 〈0.05）. There was no moderate to severe aortic insufficiency or arrhythmia. In the followed-up 1 month period after PBAV, there was only one case whose peak systolic valve gradient measured by Doppler echocardiography rose to the level of pre-PBAV.