快速MRI技术与超声在胎儿Dandy-Walker综合征中诊断价值的对比研究

Prenatal diagnosis of Dandy-Walker syndrome:fast MRI technique versus ultrasonography

目的:探讨快速MRI技术对胎儿Dandy-Walker综合征(DWS)的诊断价值,并与超声结果对照。方法:回顾性分析13例经尸检或随访证实为DWS胎儿的病例资料,所有胎儿均于行超声检查后72h内行快速MRI检查。结果:13例DWS中快速MRI明确诊断13例,并正确诊断合并的其它中枢神经系统畸形7例,与产后尸检及MRI检查结果一致。超声明确诊断6例,可疑3例,漏诊4例;明确诊断合并畸形3例,可疑2例,漏诊2例。结论:快速MRI技术对胎儿Dandy-Walker综合征及合并畸形的诊断优于超声,可作为超声检查的重要补充手段。

Objectire：To compare the accuracy of fast MRI technique and ultrasonography in detecting Dandy-Walker Syndrome （DWS）of fetus.Methods：Clinical data of 13 fetuses with DWS proved by autopsy or follow-up were retrospec-tively analyzed.The findings of fast MRI technique （T2-HASTE sequence）and ultrasonography were compared to the re-sults of autopsy and corpse MRI.Results：Compared with the final results,DWS of 13 cases,and associated other brain ab-normalities of 7 cases were shown clearly on fast MRI technology images;DWS of 6 cases was clearly demonstrated on ul-trasonography,with 3 cases being suspected and 4 cases being misdiagnosed;Of 7 cases with other brain abnormalities,3 cases were detected accurately,2 cases were suspected and 2 cases were misdiagnosed by ultrasonography.Conclusion：Fast MRI technique is superior to ultrasonography in detecting DWS with or without other brain abnormalities and can be an important supplement to ultrasonography in prenatal diagnosis of fetal brain diseases.