抑郁症发病机制研究进展

The research progress of pathogenesis in depression

抑郁症因其病因不清、致病因素复杂、发病机制不详,一直是神经科学领域的一个难题。近年来,国内外对抑郁症的研究方兴未艾,并在发病机制的研究上取得了重要进展。文中从神经生化研究、神经内分泌研究、神经可塑性研究等方面对抑郁症的发生机制主流假说进行简单阐述,以拓宽对抑郁症的认识。

Depression is a difficuh problem because of its unresolved etiology, complex pathogenic factors, and unknown pathogenesis in the field of neuroscience. In recent years, the research of the pathogenesis in depression had made important progress at home and abroad. This article elaborates the mainstream hypothesis of depression mechanism to broaden the understanding depression in the fields of neurobiochemical study, neuroendocrine and neural plasticity studies.