颅内动脉瘤开颅术后患者肺部感染的危险因素分析

Analysis of the Risk Factors of Pulmonary Infection after Craniotomy in Patients with Intracranial Aneurysms

目的:探讨颅内动脉瘤开颅术后发生肺部感染的危险因素。方法:回顾性分析在我院接受开颅手术治疗的211例颅内动脉瘤患者的性别、年龄、吸烟史、糖尿病史、高血压病史、Hunt-Hess分级、动脉瘤部位、动脉瘤直径、手术时机及术后肺部感染的情况,对可能导致肺感染的因素行X2检验及Logistic回归分析。结果:单因素分析显示影响颅内动脉瘤患者术后肺感染的因素主要包括年龄、吸烟、糖尿病、Hunt-Hess分级(P<0.05)。多因素Logistic回归分析结果显示影响颅内动脉瘤患者开颅术后发生肺部感染的因素为吸烟和Hunt-Hess分级。结论:吸烟、高Hunt-Hess分级是影响颅内动脉瘤开颅术后发生肺部感染的独立危险因素。

Objective： To analyze the risk factors of pulmonary infection after craniotomy in patients with intracranial aneurysms. Methods： The clinical data of 211 cases of patients with intracranial aneurysms who received craniotomy in our hospital were collected. Univariate analysis of variance by X2 test and multivariate analysis by multiple Logistic regression model were carried out to screen risk factors （sex, age, smoking, diabetes, hypertension, location of aneurysms, Hunt-Hess classification, time of operation and diameter of aneurysms） related to pulmonary infection after craniotomy. Results： Univariate analysis showed that age, smoking, diabetes and Hunt-Hess classification were the risk factors of pulmonary infection after craniotomy in patients with intracranial aneurysms; multivariate logistic regression analysis showed that smoking and Hunt-Hess classification were independent risk factors of pulmonary infection after craniotomy of intracranial aneurysms. Conclusion： Smoking and Hunt-Hess classification were the independent risk factors of pulmonary infection after craniotomy in patients with intracranial aneurysms.