漏斗胸术前CT肺容量测算结果与肺功能检查结果的相关性分析

Preoperative CT-based pulmonary volumetric evaluation in patients with pectus excavatum: comparison with pulmonary function test

目的通过对比CT的肺容量测算结果与常规肺功能检查结果之间的相关性,评估CT测量肺容量法的可靠性和临床意义。方法选取首都医科大学附属北京儿童医院胸外科入院治疗的共计49例漏斗胸患者,术前行肺功能检查和CT检查。应用手绘-分层测量求和法测量患者肺容量并计算其与预计值之间比例。将结果与患者常规肺功能结果进行对比。结果基于CT肺容量结果平均值低于肺功能检查结果,但与常规肺功能结果的相关性具有统计学意义:最大肺活量(maximal ventilatory capacity,VCmax)(P<0.001)、用力肺活量(forced vital capacity,FVC)(P<0.001)、肺总量(total lung capacity,TLC)(P<0.001);基于CT的肺容量实测值/预计值比例与肺功能结果相关性均有统计学意义:VCmax%(P<0.001)、FVC%(P<0.001)、TLC%(P<0.001)。结论 CT测算的肺容积结果与常规肺功能结果高度相关,CT肺容积测算法可作为临床评估漏斗胸患者肺脏容积的一种有效方法。

Objective To access the reliability of CT-based pulmonary volumetric evaluation by analyzing the correlation between lung volume calculated by CT-based pulmonary volumetric evaluation method and pulmonary function test（PFT） results. Methods This study enrolled 49 patients with pectus excavatum seen in Beijing Children＇ s Hospital. All patients had CT scan and pulmonary function test data. The CT-scan data were used to calculate lung＇s volume by handdrawn-layers summation method. The lung volume and PFT result were compared. Results The lung volume calculated by CT-based pulmonary volumetric evaluation underestimated from the PFT result of VCmax, FVC and TLC. However, the correlation between lung＇s volume and PFT result of VCmax（P〈0. 001）, FVC（P〈0. 001）, TLC （P 〈 0. 001） was significant. The correlation between value of actuality/ anticipated between lung volume and PFT results was also significant. Conclusion The lung volume calculated by CT-based pulmonary volumetric evaluation is significantly correlated with PFT results and this method is a useful way to evaluate the lung volume in clinical practice.