摘要
Dear Editor, The acrosome reaction （AR） in mamma-lian spermatozoa is a prerequisite for successful fertilization, because it leads to the release of hydrolytic enzymes from the acrosomal vesicle along with the exposure of the oocyte-recognition protein lzumo on the sperm surface （Bianchi et al., 2014）. AR mainly follows the conserved principles of calcium-regulated exocytosis in neurons/ neurosecretory cells,
