成人淋巴母细胞淋巴瘤合并急性髓细胞白血病1例并文献复习

Concurrent acute myeloid leukemia and T lymphoblastic lymphoma:a case report and review of literature

成人淋巴母细胞淋巴瘤（LBL）与急性髓细胞白血病（AML）均是血液系统高度恶性疾病,临床进展迅速,预后较差〔1〕。LBL和AML由于肿瘤细胞系别来源不同,临床大多单独起病,罕见两种疾病同时发生于同一患者。

Lymphoblastic lymphoma（LBL）and acute myeloid leukemia（AML）are highly aggressive hematologic malignancies,but concurrent LBL and AML in the same patient is rare.Here,we reported a case of 24 years old male patient with diagnosis of LBL in lymph node and AML in bone marrow respectively.The patient was treated with idarubicin and cytarabine（IA regimen）as induction therapy,but only partial remission was reached,and treatment was switched to intensive regimen（FLAG＋aclacinomycin）.After one cycle of salvage therapy with FLAG＋aclacinomycin,complete remission was attained and allogeneic stem cell transplantation was recommended as consolidation therapy.