甲磺酸伊马替尼治疗慢性粒细胞白血病引起男性乳房女性化1例报道

Imatinib mesylate caused gynaecomastia in treatment of chronic myelocytic leukemia:a case report

1病例资料 患者,男,60岁,于2003年5月起无明显诱因下自觉劳累伴消瘦,未诊治,后2004年3月因＂胃痛、发热、黑便、呕吐咖啡色液体＂至我院消化科就诊,查血常规：

Imatinib mesylate is the first-line drug in treatment of chronic myelocytic leukemia（CML）,which has an epoch-making milestone significance in the treatment of CML and is the preferred drug for the treatment of CML worldwide.However,it also has many common adverse reactions.Recently,we have found a rare case that an old man had gynaecomastia after taking imatinib mesylate for 20 months.The author writes this report in order to attract the medical workers＇ attention to such adverse reactions of imatinib mesylate.