期刊文献+

弥漫大B细胞淋巴瘤治疗后继发急性早幼粒细胞白血病1例并文献复习 被引量:3

A case report of secondary acute promyelocytic leukemia after treatment of diffuse large B-cell lymphoma and literature review
原文传递
导出
摘要 随着现代诊疗技术的提高,大剂量化疗和靶向药物的应用,淋巴瘤的生存期延长;同时反复化疗后继发的治疗相关性急性髓系白血病(AML)/骨髓增生异常综合征(MDS)发生率也不断上升,并成为非霍奇金淋巴瘤(NHL)预后不良的远期并发症之一。 A diffuse large B-cell lymphoma patient after 7cycles treatment of CHOP combined with thrombocytopenia,coagulation abnormalities was diagnosed APL after bone marrow cytology,pathology,chromosome,gene fusion.The previous treatment and chemotherapy constituted of tretinoin,daunorubicin,cytarabine and arsenic trioxide induced differentiation invalided,the patient deteriorated rapidly and died.
出处 《临床血液学杂志》 CAS 2015年第1期72-74,共3页 Journal of Clinical Hematology
关键词 非霍奇金淋巴瘤 白血病 早幼粒细胞 急性 继发 non-Hodgkin's lymphoma acute promyelocytic leukemia secondary
  • 相关文献

参考文献6

二级参考文献51

  • 1江志生,何春娜,王沁,周红,李达,吴顺杰.乳腺癌继发急性早幼粒细胞白血病持续完全缓解五年一例[J].白血病.淋巴瘤,2006,15(2):157-157. 被引量:5
  • 2邓晓辉,卞锦国,严云,梁辉.乳腺癌化疗后继发急性髓性/自然杀伤细胞白血病1例及文献复习[J].实用医学杂志,2007,23(5):706-708. 被引量:4
  • 3Myers MP, Stolarov JP, Eng C, et al. PTEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase [J]. Proc Natl Acad Sci U S A, 1997,94(17) : 9052-9057.
  • 4Li J, Yen C, Liow D, et al. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer [J]. Science, 1997, 275(5308): 1943-1947.
  • 5Dahia PL, Aguiar RC, Alberta J, et al. PTEN is inversely correlated with the cell survival factor Akt/PKB and is inactivated via muhiple mechanisms in hematological malignancies [ J]. Hum Mol Genet, 1999, 8(2) : 185-193.
  • 6Datta SR, Brunet A, Greenberg ME. Cellular survival: a play in three Akts [J]. Genes Dev, 1999, 13(22) : 2905-2927.
  • 7Shen YN, Zhang L, Gan Y, et al. Up-regulation of PTEN (phosphatase and tensin homolog deleted on chromosome ten) mediates p38 MAPK stress signal-induced inhibition of insulin signaling [J]. J Biol Chem, 2006, 281 (12) : 7727-7736.
  • 8Wee KB, Aguda BD. Akt versus p53 in a network of oncogenes and tumor suppressor genes regulating cell survival and death [ J]. Biophys J, 2006, 91 (4): 857-865.
  • 9Vasudevan KM, Gurvmunhy S, Rangnekar VM. Suppression of PTEN expression by NF-kappaB prevents apoptosis [ J]. Mol Cell Biol, 2004, 24(3): 1007-1021.
  • 10Peponi E, Drakos E, Reyes G, et al. Activation of mammalian target of rapamycin signaling promotes cell cycle progression and protects cells from apoptosis in mantle cell lymphoma [ J ]. Am J Pathol, 2006, 169(6) : 2171-2180.

共引文献31

同被引文献15

引证文献3

二级引证文献3

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部