以全身软组织广泛侵犯为首发表现的多发性骨髓瘤1例并文献复习

A case of the whole body soft tissue widespread violations as first manifestation of multiple myeloma and literature review

多发性骨髓瘤（MM）是浆细胞异常增生的恶性肿瘤,表现为骨髓内骨髓瘤细胞克隆性增殖,增生的瘤细胞广泛浸润骨骼和软组织,引起溶骨性破坏,血清出现单克隆免疫球蛋白,正常的多克隆免疫球蛋白合成受抑。通过结合骨髓细胞形态学、免疫固定电泳、血沉和β2-微球蛋白及骨骼X线检查,对MM的确诊具有重要意义。

We analyzed the diagnosis and treatment of a multiple myeloma patient with the whole body soft tissue widespread violations as first manifestation,and reviewed related literatures.The patient diagnosed as multiple myeloma after active treatment,the condition was basically stable.The whole body soft tissue widespread violation as first manifestation of multiple myeloma is rare in clinical practice and easy to be misdiagnosed.We should pay more attention to it.