吉林省结核病耐药性调查研究报告

Investigation report of drug-resistant tuberculosis in Jilin Province

目的全面了解吉林省耐多药结核病的流行现状,为吉林省制定耐多药防控相关策略措施提供科学依据。方法采用分层整群抽样方法,选择吉林省30个耐药监测点的初、复治涂阳病例;采用比例法进行药物敏感性试验。结果本次调查结果显示,吉林省初治总耐药率为33.02%,耐多药率为8.51%。多耐药率为9.62%,广泛耐药率为1.19%;复治涂阳肺结核患者总耐药率为53.94%,耐多药率为23.12%,多耐药率为15.08%,广泛耐药率为2.51%。结论吉林省是我国耐药结核病高负担省份之一,耐多药肺结核已经成为目前结核病控制工作面临的最大挑战。因此,加强现代结核病控制策略质量与肺结核病患者的管理,是提高吉林省耐药肺结核病的诊断、治疗水平的关键环节。

Objective To comprehensive understanding of the epidemic situation in Jilin province of multi drug resistant tuberculosis, established the multi drug resistance prevention and control tactics and measures to provide a scientific basis . Method By stratified cluster sampling method, thirty monitoring points of resistance selection in Jilin province, the early retreatment smear positive cases. The drug sensitivity test was carried out by using the proportional method. Result The survey results showed that, in Jilin province, the initial treatment of total drug resistance rate was 33.02%, multi drug resistant rate was 8.51%. Multi drug resistance rate was 9.62%, extensively drug resistant rate was 1.19% ; the retreatment of smear positive pulmonary tuberculosis patients in total drug resistance rate was 53.94%, multi drug resistant rate was 23.12%, multi drug resistance rate was 15.08%, extensively drug resistant rate was 2.51%. Conclusion Jilin province is one of China＇s high MDR-TB burden provinces, multi drug resistant pulmonary tuberculosis has become one of the biggest challenges currently facing the tuberculosis control work. Therefore, to strengthen the quality strategy and pulmonary tuberculosis patients management of modern tuberculosis control, is a key link to improve the diagnosis, of drug resistant tuberculosis treatment level.