抗精神病药致麻痹性肠梗阻的X线表现与临床分析

The X-ray findings and clinical analysis of antipsychotics induced paralytic ileus

目的研究分析抗精神病药致麻痹性肠梗阻的X线表现与临床征象。方法抽取本院抗精神病药致麻痹性肠梗阻患者32例,其中氯氮平、氯丙嗪致肠梗阻患者为试验组,而其他药物致病患者为对照组,分析总结其X线表现及临床征象。结果 32例患者中试验组的X线表现以小肠充气扩张、结肠扩大、出现气液平面为主且表现明显,而对照组患者X线表现则以肠鸣音减弱或消失、恶心呕吐、排便排气困难、腹部压痛或不明显等症状为主。且老人的X线表现比年轻人更明显。结论抗精神病药中以氯氮平、氯丙嗪致肠梗阻的发生率及程度最高,且年龄越大,患病概率越大。

Objective To study and analyze clinical features and the X-ray findings of antipsychotics induced paralytic ileus. Methods Collected 32 cases of paralytic intestinal obstruction caused by antipsychotics as research objects, which caused by clozapine, chlorpromazine as experimental group, and other as control group, analyzed and summarized the X-ray findings and clinical signs. Results There were mainly small intestine, colon, inflatable ex-pansion and appearance of air fluid in X-ray findings of experimental group in 32 cases of patients, while the control group patients were mainly mild symptoms, X-ray manifestations of elderly patients were more obvious than young people. Conclusion The incidence rate and degree of clozapine and chlorpromazine which induced intestinal ob-struction are the highest, the probability of illness increased which is consistent with the age.