摘要
本期,Daniel向读者推荐的文章是:在科学研究中充分使用功能原理模型。本文以帕金森氏病为例,向读者解读了:功能原理模型对研究者的重要指导作用。”功能原理模型”貌似一张张卡通画,但实际上是设计和实施一个高质量的研究项目的规划图。作者的原始构思和战略战术,往往就从这些可爱的”功能原理模型”中来。本文将有助于读者和研究人员,保持清醒头脑开展实验设计。
The use of functional, schematic models in any field of research has proven to be an invaluable tool for developing no- vel ideas and is often instrumental in taking research ideas in new directions. In this edition, I use the classic func- tional model of the basal ganglia circuitry, which was originally described in the late 1980S(Albin et al. , 1989), as a prime example for what has been used for major developments in the research of neural networks for processing movement, particularly emphasising its use for understanding the pathogenesis of Parkinson' s disease (PD).
出处
《中国实验动物学报》
CAS
CSCD
2014年第6期114-114,I0001,共2页
Acta Laboratorium Animalis Scientia Sinica