摘要
糖蛋白激素是人体内一类重要激素家族,由4个成员构成—促卵泡激素(FSH)、促黄体素(LH)、促甲状腺激素(TSH)和绒毛膜促性腺激素(CG)。这些激素结构相似,但功能各异。主要从结构方面对糖蛋白激素的亚基装配、受体识别及长效化改造进行分析综述。
Glycoprotein hormone （GPH） is a kind of important human hormones family, which consist of four members of-FSH, LH, CG and TSH. The structures of these GPHs are similar, but the functions are different. This paper mainly reviewed on the structure, subunits assembly, receptors recognition, and long-acting engineering of glycoprotein hormones.
出处
《生物技术进展》
2015年第1期22-28,共7页
Current Biotechnology
基金
国家863计划项目(2012AA02A306)资助
关键词
糖蛋白激素
结构
受体识别
长效化改造
glycoprotein hormone
structure
receptor recognition
long-acting engineering
