摘要
目的探讨奥沙利铂、5-氟尿嘧啶和亚叶酸钙组成的m FOLFOX6方案联合复方斑蝥胶囊在结肠癌术后辅助化疗中的疗效。方法 50例结肠癌患者均采用m FOLFOX6化疗,随机分为两组,观察组同步口服复方斑蝥胶囊。结果两组患者血常规各项指标变化比较,差异有统计学意义(P<0.05)。在1、2个周期化疗后,观察组的外周血T细胞亚群水平较治疗前明显增高,差异有统计学意义(P<0.05)。结论复方斑蝥胶囊联合m FOLFOX6方案作为结肠癌术后辅助化疗,可降低粒细胞减少和贫血的发生,提高患者机体免疫力。
Objective To observe the efficacy of m FOLFOX6 regimen combined with Fufangbanmao capsule for adjuvant chemotherapy in colon cancer.Methods A total of 50 patients were treated with m FOLFOX6 chemotherapy,and 50 patients were randomly divided into two groups,the observation group oraled Fufangbanmao capsule.Results The indicators of blood count changed in the patients,the difference was statistically significant(P〈0.05).After 1 and 2 cycles of chemotherapy,the value of T cell subsets was higher than before treatment(P〈0.05).Conclusion The Fufangbanmao capsule(Kang Saidi) combined with m FOLFOX6 for adjuvant chemotherapy in colon cancer,could reduce the occurrence of neutropenia and anemia,and improve patients' immunity.
出处
《中国肿瘤临床与康复》
2015年第1期50-52,共3页
Chinese Journal of Clinical Oncology and Rehabilitation
关键词
复方斑蝥胶囊
辅助化疗
结肠肿瘤
Fufangbanmao capsule
Adjuvant chemotherapy
Colon neoplasms