复方斑蝥胶囊联合化疗在结肠癌术后辅助化疗中的疗效观察

The efficacy of Fufangbanmao capsules combined with m FOLFOX6 regimen for adjuvant chemotherapy in patients with colon cancer

目的探讨奥沙利铂、5-氟尿嘧啶和亚叶酸钙组成的m FOLFOX6方案联合复方斑蝥胶囊在结肠癌术后辅助化疗中的疗效。方法 50例结肠癌患者均采用m FOLFOX6化疗,随机分为两组,观察组同步口服复方斑蝥胶囊。结果两组患者血常规各项指标变化比较,差异有统计学意义(P<0.05)。在1、2个周期化疗后,观察组的外周血T细胞亚群水平较治疗前明显增高,差异有统计学意义(P<0.05)。结论复方斑蝥胶囊联合m FOLFOX6方案作为结肠癌术后辅助化疗,可降低粒细胞减少和贫血的发生,提高患者机体免疫力。

Objective To observe the efficacy of m FOLFOX6 regimen combined with Fufangbanmao capsule for adjuvant chemotherapy in colon cancer.Methods A total of 50 patients were treated with m FOLFOX6 chemotherapy,and 50 patients were randomly divided into two groups,the observation group oraled Fufangbanmao capsule.Results The indicators of blood count changed in the patients,the difference was statistically significant（P〈0.05）.After 1 and 2 cycles of chemotherapy,the value of T cell subsets was higher than before treatment（P〈0.05）.Conclusion The Fufangbanmao capsule（Kang Saidi） combined with m FOLFOX6 for adjuvant chemotherapy in colon cancer,could reduce the occurrence of neutropenia and anemia,and improve patients＇ immunity.