摘要
目的探讨护理干预对肾癌术后重组人干扰素α-2b治疗效果的影响。方法将94例采用根治术治疗的肾癌患者随机分为对照组和干预组,每组47例。所有患者在术后给予重组人干扰素α-2b治疗,在此期间,对照组给予常规护理,干预组在常规护理的基础上给予护理干预。比较两组患者的临床指征改善情况、治疗和护理效果以及术后不良反应的发生情况。结果干预组患者的退热时间、白细胞恢复正常时间和术后住院时间均小于对照组(P<0.05)。干预组患者的术后不良反应发生率为4.3%,低于对照组的17.0%(P<0.05)。干预组和对照组患者治疗和护理的有效率分别为97.9%和93.6%,差异无统计学意义(P>0.05)。结论肾癌根治术后应用重组人干扰素α-2b治疗时,给予患者有效的护理干预,可明显缩短术后治疗时间,改善患者的临床症状,降低不良反应的发生率,值得临床推广。
Objective To investigate the effect of nursing intervention on patients treated with recombinant interferon α-2b(r INFα-2b) after radical nephrectomy.Methods 94 patients after radical nephrectomy were randomly divided into the control group(47 cases) and the intervention group(47 cases).All of the patients were treated with recombinant human interferon α-2b,the control group was given conventional nursing,while the intervention group was given both conventional nursing and intervention nursing.The clinical effect and adverse reactions of the two groups were observed and compared.Results The time of fever relieving,recovery normal of leukocyte and stay in hospital of the intervention group were less than the control group(P〈0.05).The incidence of adverse effect of the intervention group and the control group were4.3% and 17.0%,respectively(P〈0.05).However,the total response rate of the two groups were consistent(97.9% vs 93.6%,P〈0.05).Conclusion The implementation of nursing intervention on patients giving r INFα-2b after radical nephrectomy can shorten the postoperative time,improve the clinical symptoms and reduce the adverse reactions.
出处
《中国肿瘤临床与康复》
2015年第1期95-97,共3页
Chinese Journal of Clinical Oncology and Rehabilitation
关键词
护理干预
肾肿瘤
外科手术
重组人干扰素Α-2B
Nursing intervention
Kidney neoplasms
Surgical procedures
operative
rINFα-2b