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Prime-boost免疫策略在抗顶复门原虫感染中的应用 被引量：2

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摘要 顶复门原虫对人类健康以及畜牧业生产危害严重,其入侵会激发机体的抵御机制,引起机体促炎反应,进而给机体造成伤害。使用基因工程疫苗可增强机体的体液免疫和细胞免疫,从而阻止虫体入侵。在抗寄生虫感染过程中,免疫策略的选择至关重要,初免-加强(Primeboost)免疫策略可以使疫苗刺激机体产生更强、更持久的体液和细胞免疫反应,其不仅在抗病毒、细菌感染过程中取得长足发展,也在抗寄生虫感染过程中得到广泛应用。
作者 陈海宁 戚南山 廖申权 吴彩艳 李娟 吕敏娜 仝宗喜 孙铭飞
机构地区 河南农业大学牧医工程学院 广东省农业科学院动物卫生研究所
出处 《畜牧与兽医》 北大核心 2015年第1期130-134,共5页 Animal Husbandry & Veterinary Medicine
基金 国家自然科学基金(31201902 31302086 31402186) 珠江科技新星项目(2012J2200059) 广东省农业攻关项目(2012A020100001) 广州市产学研合作专项(2014Y2-00003)
关键词 顶复门原虫 PRIME-BOOST 寄生虫感染 免疫反应
分类号 S855.9 [农业科学—临床兽医学]
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参考文献42

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二级参考文献110

共引文献21

同被引文献21

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畜牧与兽医
2015年 第1期

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