单、多发性结直肠息肉患者的人群特征比较

Comparison of population characteristics of patients with single and multiple colorectal polyps

目的比较单、多发性结直肠息肉患者的人群特征。方法选取2012年10月至2014年3月行电子结肠镜检查并经病理活组织检查(活检)确诊为结直肠息肉的患者为调查对象,根据息肉数目分为单发性息肉组和多发性息肉组,收集患者的性别、年龄、BMI、饮食习惯、个人生活方式、烟酒嗜好、疾病史、手术史、家族史等人群特征资料。应用多因素非条件Logistic回归分析人群特征与多发性结直肠息肉的相关性。结果共收集241例患者,年龄≥50岁(OR=3.75)、吸烟(OR=3.73)与多发性结直肠息肉呈正相关(P<0.05)。结论年龄≥50岁、吸烟为多发性结直肠息肉的危险因素。

Objective To compare the population characteristics of patients with single and multiple colorectal polyps.Methods Patients diagnosed with colorectal polys by electronic colonoscopy and pathological examination （biopsy）between October,2012 and March,2014 were enrolled in this study.All cases were divided into single and multiple polyps groups.Patients’sex,age,body mass index,dietary habits,lifestyles, smoking,drinking,medical history,surgical history and family history were collected.Multivariate non-condi-tional logistic regression analysis was adopted to evaluate the correlation between these characteristics and mul-tiple polyps.Results A total of 241 patients were finally enrolled in this survey.Compared to single polyp, age≥50 years （OR =3.75）and smoking （OR =3.73）were positively associated with the incidence of multiple polys （P 〈0.05）.Conclusion Age≥50 years and smoking are risk factors of the incidence of multiple colorectal polys.