摘要
目的研究吴茱萸Euodia rutaecarpa的化学成分。方法采用硅胶柱色谱、ODS柱色谱、Sephadex LH-20柱色谱等多种色谱手段进行分离纯化,利用波谱学方法鉴定化合物的结构。结果从吴茱萸75%乙醇提取物中分离得到8个化合物,分别鉴定为芥子醇9-O-阿魏酰基-4-O-β-D-葡萄糖苷(1)、3-O-阿魏酰基奎尼酸甲酯(2)、咖啡酸(3)、阿魏酸(4)、对羟基桂皮酸(5)、4-甲氧基苯甲醇(6)、3,4-二羟基苯甲酸(7)、7-羟基香豆素(8)。结论化合物1为1个新的苯丙素苷类化合物,命名为新吴茱萸苷。化合物2、3、6、7为首次从吴茱萸属植物中分离得到。
Objective To study the chemical constituents from the 75% ethanol extract of Euodia rutaecarpa. Methods Chromatographic methods, such as silica gel, ODS, and Sephadex LH-20 column chromatography, were used for the isolation and purification. The structures were identified on the basis of spectroscopic analysis. Results Eight compounds were isolated from the 75% ethanol extract of E. rutaecarpa, and were identified as sinapyl alcohol 9-O-feruloyl-4-O-β-D-glucopyanoside（1）, 3-Ocaffeoylquinic acid methyl ester（2）, caffeic acid（3）, ferulic acid（4）, p-hydroxycinnamic acid（5）, 4-methoxybenzylalcohol（6）, 3, 4-dihydroxy-benzoic acid（7）, and 7-hydroxy coumarin（8）. Conclusion Compound 1 is a new phenylpropanoid glycoside named neoeuodiside, and compounds 2, 3, 6, and 7 are isolated from the plants of Euodia J. R. et G. Forst. for the first time.
出处
《中草药》
CAS
CSCD
北大核心
2015年第1期15-18,共4页
Chinese Traditional and Herbal Drugs
关键词
吴茱萸
苯丙素苷
新吴茱萸苷
3-O-阿魏酰基奎尼酸甲酯
咖啡酸
4-甲氧基苯甲醇
Euodia rutaecarpa（Juss.） Benth
phenylpropanoid glycoside
neoeuodiside
3-O-caffeoylquinic acid methyl ester
caffeic acid
4-methoxybenzylalcohol
