探讨甲状腺自身抗体阳性甲亢病的^(131)I治疗与甲减关系

The Treatment of ^(131)I in Thyrotoxicosis with Thyroid Autoantibody Positive and the Relationship With Hypothyroidism

目的探讨甲状腺自身抗体阳性甲亢病的131I治疗与甲减关系。方法选取我院200例确诊为甲亢病且使用131I治疗的患者,根据其甲状腺自身抗体的阳性、阴性,分为观察组(112例)和对照组(88例),观察和比较两组患者在使用131I治疗后的效果。结果观察组患者在131I治疗后的不同时期,治愈率均高于对照组,但是观察组患者在治疗后甲减的出现率明显比对照组高(P<0.005)。结论在使用131I治疗时,对甲状腺自身抗体阳性的甲亢病患者,需要减少用量。增加对甲亢病患者的甲状腺自身抗体的常规检查,以降低甲减的发生率。

ObjectiveTo investigate the effect of positive thyroid autoantibodies of hyperthyroidism and hypothyroidism treated with ^131I. Methods 200 cases in our hospital were diagnosed as hyperthyroidism disease and treated with ^131 I, according to the positive, negative thyroid autoantibodies, divided into the observation group （112 cases） and control group （88 cases）, observed and compared the two groups of therapeutic effect.ResultsThe observation group patients in different period after treatment, the cure rate was higher than that of control group, but in the observation group were seen after treatment of hypothyroidism was significantly higher than the control group （P〈0.005）.Conclusion The use of ^131 I therapy on thyroid autoantibodies positive hyperthyroidism patients, we need to reduce the amount. Increase the routine examination of hyperthyroidism in patients with thyroid autoantibodies in order to reduce the incidence of hypothyroidism.